As we certainly know by now (whether we want to or not), medical inoculation refers to a set of methods of artificially inducing immunity against infectious diseases. While our immune systems are extremely adept at fighting viruses, they sometimes need a helping hand. In this Thursday Thought, I draw the analogy of inoculation methodologies and organisational (and even individual) transformation journeys. In particular, I focus on the multi-dose approach, as we are experiencing today with the Covid-19 vaccine rollout.